| Geeta Shukla* and Neeraj Pahuja |
Department of Microbiology, Panjab University, Chandigarh - 160 014
*Corresponding author : firstname.lastname@example.org
The severity of malaria infection during pregnancy is correlated with the
parasitaemic levels, placental infection and foetal abnormalities. Malaria
is more severe and frequent in pregnant woman, than in non-pregnant women.
Placenta of pregnant Plasmodium berghei infected mice showed alterations
on surface of placenta. Trophoblastic membrane of the infected placenta
was severely damaged. The bulbous microvillus ends were severely necrosed
that resulted in aggregation of trophoblastic membrane. These altered placental
surface may be responsible for internal damage of placenta which in turn
might be responsible for abnormal foetal developments like pre-term delivery,
low body weight of new born, foetal death or abortions in pregnant women.
Key words:. Plasmodium berghei, placenta, pregnancy, malaria..